UVa Course Catalog (Unofficial, Lou's List)
Complete Catalog for the Biomedical Engineering Department    
Class Schedules Index Course Catalogs Index Class Search Page
These pages present data mined from the University of Virginia's student information system (SIS). I hope that you will find them useful. — Lou Bloomfield, Department of Physics
Biomedical Engineering
BME 1501Special Topics (1.00)
Offered
Fall 2017
Student led special topic courses which vary by semester
BME 2000Biomedical Engineering Design and Discovery (3.00)
Offered
Fall 2017
Provides overview of the BME discipline and major sub-disciplines (biomechanics, genetic engineering, tissue engineering, bioelectricity, imaging, cellular engineering, computational systems biology), covers conceptual and detail design processes, and introduces quantitative tools utilized throughout the BIOM curriculum. A major focus of the class will be formulation and execution of a design project. Prerequisite: BME 2101, BME 3315, AND second-year status in Biomedical Engineering OR instructor permission.
BME 2101Physiology I for Engineers (3.00)
Offered
Fall 2017
We learn how excitable tissue, nerves and muscle, and the cardiovascular and respiratory systems function. You will develop an understanding of mechanisms, with an introduction to structure, an emphasis on quantitative analysis, and integration of hormonal and neural regulation and control. Prerequisites: intro courses in biology, chemistry, physics & calculus (BIOL 2010, CHEM 1610, PHYS 1425, APMA 1110 or similar) or instructor permission.
BME 2102Physiology II (3.00)
Introduces the physiology of the kidney, salt and water balance, gastrointestinal system, endocrine system, and central nervous system, with reference to diseases and their pathophysiology. (Circulation and respiration are covered in the fall semester course, BME 2101). Prerequisite: BME 2101 or instructor permission.
BME 2104Cell and Molecular Biology for Engineers (3.00)
Offered
Fall 2017
Introduces the fundamentals of cell structure and function, emphasizing the techniques and technologies available for the study of cell biology. A problem-based approach is used to motivate each topic. Divided into three general sections: cell structure and function includes cell chemistry, organelles, enzymes, membranes, membrane transport, intracellular compartments and adhesion structures; energy flow in cells concentrates on the pathways of glycolysis and aerobic respiration; information flow in cells focuses on modern molecular biology and genetic engineering, and includes DNA replication, the cell cycle, gene expression, gene regulation, and protein synthesis. Also presents specific cell functions, including movement, the cytoskeleton and signal transduction. Prerequisite: CHEM 1610 or instructor permission.
BME 2220Biomechanics (3.00)
Offered
Fall 2017
Introduction to principles of continuum mechanics of biological tissues and systems. Topics include development of selected fundamental methods and results from statics and strength of materials, continuum mechanics, free-body diagrams, and constitutive equations of biological materials. Properties of blood vessels, heart, bone, cartilage, ligaments, tendons, blood, and other tissues. Mechanical basis and effects of pathology and trauma. Prerequisites: APMA 2130, BME 2101, or permission of instructor
BME 2315Computational Biomedical Engineering (3.00)
Offered
Fall 2017
Introduces computational techniques for solving biomedical engineering problems & constructing models of biologic processes. Numerical techniques include regression, interpolation, differentiation, integration, root finding, systems of equations, optimization and approaches to ordinary differential equations. Applications include bioreactors, biotransport, pharmacokinetics & biomechanics. Prereq: APMA 2120 & CS 1110; recommended co-req APMA 2130.
Course was offered Fall 2016, Fall 2015, Fall 2014
BME 3030Design and Innovation in Medicine (3.00)
A project-based grounding in biomedical product design, with emphasis on clinical immersion and topics including design fundamentals, problem/needs identification, delineation of realistic constraints and product specifications, intellectual property, market analysis, entrepreneurship, specific advanced design topics, business plan development, venture funding, and medical product testing methods.REQ: instructor permission .
BME 3080Biomedical Engineering Integrated Design and Experimental Analysis (IDEAS) Laboratory I (4.00)
Offered
Fall 2017
First half of a year-long course to integrate concepts and skills from prior courses in order to formulate and solve problems in biomedical systems, including experimental design, performance, and analysis. Lab modules include testing in tissues/cells and manipulation of molecular constituents of living systems to determine their structural and functional characteristics for design of therapeutic or measurement systems. Methods include biochemical, physiological, cell biology, mechanical, electrical and computer, systems, chemical, imaging, and other approaches. Prerequisite: APMA 2120, APMA 2130, APMA 3110, BME 2101, BME 2104, and BME 2220, or instructor permission; corequisite: BME 3310 or instructor permission.
BME 3090Biomedical Engineering Integrated Design and Experimental Analysis (IDEAS) Laboratory II (4.00)
Second half of a year-long course to integrate the concepts and skills from prior courses in order to formulate and solve problems in biomedical systems, including experimental design, performance, and analysis. Lab modules include testing in tissues/cells and manipulation of molecular constituents of living systems to determine their structural and functional characteristics and to design measurement or therapeutic systems. Methods include biochemical, physiological, cell biology, mechanical, electrical and computer, systems, chemical, imaging, and other approaches. Prerequisite: BIOM 3080 or instructor permission.
BME 3240Biotransport (3.00)
Offered
Fall 2017
Biotransport in biological living systems is a fundamental phenomenon important in all aspects of the life cycle. Course will introduce principles and application of fluid and mass transport processes in cell, tissue and organ systems. Topics include, introduction to physiological fluid mechanics in the circulation and tissue, fundamentals of mass transport in biological systems, effects of mass transport and biochemical interactions at the cell and tissue scales, and fluid and mass transport in organs.
BME 3310Biomedical Systems Analysis and Design (3.00)
Offered
Fall 2017
Presents the analytical tools used to model signals and linear systems. Specific biomedical engineering examples include multicompartment modeling of drug delivery, modeling of dynamic biomechanical systems, and electrical circuit models of excitable cells. Major topics include terminology for signals and systems, convolution, continuous time Fourier transforms, Laplace transforms, electrical circuits with applications to bioinstrumentation and biosystems modeling, and applications of linear system theory. Students cannot receive credit for both this course and ECE 3750. Prerequisite: APMA 2130, CS 1110 or instructor permission.
BME 3636Neural Network Models of Cognition and Brain Computation (3.00)
An introductory course to neural networks research, specifically biologically-based networks that reproduce cognitive phenomena. The goal of this course is to teach the basic thinking and methodologies used in constructing and understanding neural-like networks. Cross-listed as NESC 5330. CS 1110; and BIOM 2101; or permission of the instructor.
BME 4063Biomedical Engineering Capstone Design I (3.00)
Offered
Fall 2017
A year-long design project in biomedical engineering required for BME majors. Students select, formulate, and solve a biomedically relevant design problem whose deliverables include a device, therapeutic, and/or system. Projects may be sponsored by BME faculty, medical doctors, and/or companies. Students may work on their own with outside team members when appropriate or with other SEAS students in integrative teams. Prerequisite: APMA 2120, 2130, 3110, BME 2101, 2104, 3080, 3310, fourth-year standing in BME major, or instructor permission.
BME 4064Biomedical Engineering Capstone Design II (3.00)
Second half of a year-long design project in biomedical engineering required for BME majors. Students select, formulate, and solve a biomedically relevant design problem whose deliverables include a device, therapeutic, and/or system. Projects may be sponsored by BME faculty, medical doctors, and/or companies. Students may work on their own with outside team members when appropriate or with other SEAS students in integrative teams. Prerequisite: APMA 2120, 2130, 3110, BME 2101, 2104, 3080, 3310, fourth-year standing in BME major, or instructor permission.
BME 4280Motion Biomechanics (3.00)
Focuses on the study of forces (and their effects) that act on the musculoskeletal structures of the human body. Based on the foundations of functional anatomy and engineering mechanics (rigid body and deformable approaches); students are exposed to clinical problems in orthopedics and rehabilitation. Prerequisite: BME 2101, 2220, or instructor permission.
BME 4414Biomaterials (3.00)
Offered
Fall 2017
This course will provide an introduction to biomaterials science and biological interactions with materials, focusing on clinical applications using FDA approved materials. Areas of concentration will include the use of polymers and ceramics in biomaterials today, tissue response to materials, and drug delivery & diagnostic applications. Prerequisite: BME 2104 and BME 2220 or equivalent
BME 4417Tissue Engineering (3.00)
Introduces the fundamental principles of tissue engineering. Topics: tissue organization and dynamics, cell and tissue characterization, cell-matrix interactions, transport processes in engineered tissues, biomaterials and biological interfaces, stem cells and interacting cell fate processes, and tissue engineering methods.Prerequisites: CHEM 1620, APMA 2130, and an introductory course in cell and molecular biology or instructor permission.
BME 4550Special Topics in Biomedical Engineering (3.00)
Offered
Fall 2017
Applies engineering science, design methods, and system analysis to developing areas and current problems in biomedical engineering. Topics vary by semester. Recent topics include Medical Imaging Systems Theory, BME Advanced Design, BME Electronics Lab, and Systems Biology Modeling and Experimentation. Prerequisite: third- or fourth-year standing and instructor permission.
BME 4641Bioelectricity (3.00)
Offered
Fall 2017
Studies the biophysical mechanisms governing production and transmission of bioelectric signals, measurement of these signals and their analysis in basic and clinical electrophysiology. Introduces the principles of design and operation of therapeutic medical devices used in the cardiovascular and nervous systems. Includes membrane potential, action potentials, channels and synaptic transmission, electrodes, electroencephalography, electromyography, electrocardiography, pacemakers, defibrillators, and neural assist devices. Prerequisite: BME 3310 or ECE 2630, BME 2101, or instructor permission.
BME 4783Medical Imaging Modalities (3.00)
An overview of modern medical imaging modalities with regard to the physical basis of image acquisition and methods of image reconstruction. Topics cover the basic engineering and physical principles underlying the major medical imaging modalities: x-ray (plain film, mammography, and computed tomography (CT)), nuclear medicine (positron-emission tomography (PET) and single-photo-emission computed tomography (SPECT)), ultrasound, and magnetic resonance imaging (MRI). Prerequisite: BME 3310 or ECE 3750, or instructor permission.
BME 4784Medical Image Analysis (4.00)
Introduces the fundamental principles of medical image analysis and visualization. Focuses on the processing and analysis of ultrasound, MR, and X-ray images for the purpose of quantitation and visualization to increase the usefulness of modern medical image data. Includes image perception and enhancement, 2-D Fourier transform, spatial filters, segmentation, and pattern recognition. A weekly lab develops skill in computer image analysis with the KHOROS system. Prerequisite: BME 3310, ECE 3750, or instructor permission.
BME 4806Biomedical Applications of Genetic Engineering (3.00)
Offered
Fall 2017
Provides biomedical engineers with a grounding in molecular biology and a working knowledge of recombinant DNA technology, thus establishing a basis for the evaluation and application of genetic engineering in whole animal systems. Beginning with the basic principles of cell structure and function, this course examines the use of molecular methods to study gene expression and its critical role in health and disease. Topics include DNA replication, transcription, translation, methods for studying genes and gene expression at the mRNA and protein levels, methods for mutating genes and introducing genes into cells, methods for creating genetically-engineered mice and methods for accomplishing gene therapy by direct in vivo gene transfer. Prerequisite: BME 2101, 2102, and 2104, or CHE 2246, and third- or fourth-year standing, or instructor permission.
BME 4890Nanomedicine (3.00)
Offered
Fall 2017
Students will design treatment strategies for cancer and cardiovascular disease based on molecular bioengineering principles. Special topics will include design of nanoparticle drug and gene delivery platforms, materials biocompatibility, cancer immunotherapy, and molecular imaging. Prerequisite: BME 2104 or CHE 2246, BME 2220, fourth-year standing, or instructor permission; Recommended: BME 2240
BME 4993Independent Study (1.00 - 3.00)
In-depth study of a biomedical engineering area by an individual student in close collaboration with a departmental faculty member. Requires advanced analysis of a specialized topic in biomedical engineering that is not covered by current offerings. Requires faculty contact time and assignments comparable to regular course offerings. Prerequisite: instructor permission.
BME 4995Biomedical Engineering Advanced Projects (1.00 - 3.00)
Offered
Fall 2017
A year-long research project in biomedical engineering conducted in consultation with a department faculty advisor; usually related to ongoing faculty research. Includes the design, execution, and analysis of experimental laboratory work and computational or theoretical computer analysis of a problem. Requires a comprehensive report of the results. Prerequisite: third- or fourth-year standing, and instructor permission.
BME 6026Quantitative Models of Human Perceptual Information Processing (3.00)
An introduction to the measurement and modeling of human perceptual information processing, with approaches from neurophysiology to psychophysics, for the purposes of system design. Measurement includes classical psychophysics, EEG field potentials, and single-neuron recordings. Modeling includes signal detection theory, neuronal models (leaky integrate-and-fire, Hodgkin-Huxley, and models utilizing regression, probability, and ODEs). Prerequisite: Graduate standing; background courses in ordinary differential equations, statistics and probability; or consent of instructor.
Course was offered Spring 2013
BME 6030Design and Innovation in Medicine (3.00)
A project-based grounding in biomedical product design, with emphasis on clinical immersion and topics including design fundamentals, problem/needs identification, delineation of realistic constraints and product specifications, intellectual property, market analysis, entrepreneurship, specific advanced design topics, business plan development, venture funding, and medical product testing methods. Prerequisite: Instructor Permission
Course was offered Spring 2017, Spring 2016
BME 6060Biomedical Innovation (3.00)
Multi-disciplinary problem solving is an essential component of innovation, especially in complex systems such as health care. The overall goal of this course is to provide graduate students with supervised real-world experience identifying problems in health care and developing solutions using a collaborative approach. Prerequisites: Graduate standing in any participating school and instructor permission.
Course was offered Fall 2010
BME 6101Physiology I for Engineers (3.00)
Offered
Fall 2017
Introduces fundamental concepts of cellular physiology; applies quantitative engineering analysis to intra- and intercellular signaling and mechanical systems relevant to organ physiology and pathology; teaches students to learn to think critically about the physiology and cell biology literature. Prerequisite: BME 2104 or equivalent; proficiency with ODEs.
BME 6102Engineering Physiology II (3.00)
Second part of physiology sequence for engineering students; focuses on physiology of the cardiovascular, pulmonary, renal, and nervous systems; emphasizes quantitative analysis of organ function, particularly the use of mathematical models to identify and understand key underlying mechanisms. Prerequisite: BME 6101
BME 6103Physiology I (3.00)
We learn how excitable tissue, nerves and muscle, and the cardiovascular and respiratory systems function. You will develop an understanding of mechanisms, with an introduction to structure, an emphasis on quantitative analysis, and integration of hormonal and neural regulation and control. Prerequisites: introductory undergraduate courses in biology, chemistry, physics and calculus or instructor permission.
BME 6104Physiology and Pathophysiology (3.00)
This course will emphasize a fundamental understanding of physiology with a focus on mechanisms, and continues the coverage of major systems from BIOM 6103. Studies the renal, gastrointestinal, endocrine, and central nervous systems. Integration of function from molecule to cell to organ to body. Includes some functional anatomy. Quantitative understanding of problems like salt and water balance through class work and homework sets. Five lectures on specific diseases and their pathophysiology. Prerequisite: BME 6103 or instructor permission.
BME 6280Motion Biomechanics (3.00)
Focuses on the study of forces (and their effects) that act on the musculoskeletal structures of the human body. Based on the foundations of functional anatomy and engineering mechanics (rigid body and deformable approaches); students are exposed to clinical problems in orthopedics and rehabilitation. Cross-listed as AM 6280. Prerequisite: BME 6103.
BME 6310Computation and Modeling in Biomedical Engineering (3.00)
Offered
Fall 2017
The principle objective of this course is to instruct graduate students on fundamental mathematical, modeling, and computational principles of relevance in biomedical engineering. The course is structured to provide lecture material, biomedical examples that use modeling and computation, and homework/exams that strengthen the mathematical and computational foundation of the graduate students. Prerequisites: 1. BME 6101: Physiology I (or equivalent) 2. SEAS grad student status 3. Some previous exposure to probability-statistics, Fourier analysis, and linear systems 4. Or instructor permission
BME 6311BME Measurement Principles (3.00)
Students will gain a fundamental understanding of the theoretical principles underlying biomedical measurements. Topics are organized sequentially from signal initiation through signal processing to downstream statistical analysis of measurements. Students will be exposed to the practical implementation of general principles through homework assignments that involve the analysis and evaluation of molecular, cellular, and clinical measurements. Prerequisites: 1. BME 6101: Physiology I (or equivalent) 2. SEAS graduate student status 3. Some previous exposure to probability-statistics, Fourier analysis, and linear systems 4. Or Instructor Permission
BME 6550Special Topics in Biomedical Engineering (1.00 - 3.00)
Offered
Fall 2017
Applies engineering science, design methods, and system analysis to developing areas and current problems in biomedical engineering. Topics vary by semester.
BME 7370Quantitative Biological Reasonsing (3.00)
Provides students with a quantitative framework for identifying and addressing important biological questions at the molecular, cell, and tissue levels. Focuses on the interplay between methods and logic, with an emphasis on the themes that emerge repeatedly in quantitative experiments. Prerequisites: BME 6101 (or equivalent), SEAS graduate student status, or instructor permission.
BME 7641Bioelectricity (3.00)
Offered
Fall 2017
Studies the biophysical mechanisms governing production and transmission of bioelectric signals, measurement of these signals and their analysis in basic and clinical electrophysiology. Introduces the principles of design and operation of therapeutic medical devices used in the cardiovascular and nervous systems. Prerequisite: BME 6310 or instructor permission.
BME 7782Medical Imaging Systems Theory (3.00)
Develops an intuitive understanding of the mathematical systems theory needed to understand and design biomedical imaging systems, including ultrasound, magnetic resonance imaging and computed tomography. Topics will include multidimensional Fourier transform theory, image reconstruction techniques, diffraction theory, and Fourier optics. Prerequisite: BME 6310 or equivalent exposure to linear systems theory or instructor permission.
BME 7784Medical Image Analysis (3.00)
Comprehensive overview of medical image analysis and visualization. Focuses on the processing and analysis of these images for the purpose of quantitation and visualization to increase the usefulness of modern medical image data. Topics covered involve image formation and perception, enhancement and artifact reduction, tissue and structure segmentation, classification and 3-D visualization techniques as well as pictures archiving, communication and storage systems. Involves 'hands-on' experience with homework programming assignments. Prerequisite: BIOM 6310 and ECE 6782 or instructor permission.
BME 7806Biomedical Applications of Genetic Engineering (3.00)
Offered
Fall 2017
Provides biomedical engineers with a grounding in molecular biology and a working knowledge of recombinant DNA technology, thus establishing a basis for the evaluation and application of genetic engineering in whole animal systems. Beginning with the basic principles of genetics, this course examines the use of molecular methods to study gene expression and its critical role in health and disease. Topics include DNA replication, transcription, translation, recombinant DNA methodology, methods for analyzing gene expression (including microarray and genechip analysis), methods for creating genetically-engineered mice, and methods for accomplishing gene therapy by direct in vivo gene transfer. Prerequisite: BME 6103, undergraduate-level cell and/or molecular biology course. (e.g., BME 2104) or instructor permission. Suggested preparation: biochemistry, cell biology, genetics, and physiology..
BME 8000TNon-UVa Transfer/Test Credit Approved (1.00 - 48.00)
Non-UVa Transfer/Test Credit Approved
BME 8315Systems Bioengineering and Multi-Scale Models (3.00)
Offered
Fall 2017
In this course students will gain working knowledge of constructing mathematical and computational models of biological processes at many levels of organizational scale from genome to whole-tissue. Students will rotate through several modules where they will hear lectures, read literature, and participate in discussions focused on the various modeling techniques. Prerequisites: BME 6101/6102: Physiology (or equivalent); 2. One of the following courses in cellular and/or molecular biology: BME 2104: Cell and Molecular Biology for Engineers, BME 7806: Genetic Engineer.
BME 8550Advanced Topics in Biomed Engineering (3.00)
Applies engineering science, design methods, and system analysis to developing areas and current problems in biomedical engineering. Topics vary by semester.
Course was offered Fall 2015, Fall 2011, Fall 2010, Fall 2009
BME 8730Diagnostic Ultrasound Imaging (3.00)
Underlying principles of array based ultrasound imaging. Physics and modeling techniques used in ultrasound transducers. Brief review of ID circuit transducer models. Use of Finite Element techniques in transducer design. Design considerations for 1.5D and 2D arrays will be reviewed. Diffraction and beamforming will be introduced starting from Huygen's principle. FIELD propagation model will form an important part of the class. In depth discussion of various beamforming and imaging issues such as sidelobes, apodization, grating lobes, resolution, contrast, etc. The course addresses attenuation, time-gain-compensation and refraction. Finally, speckle statistics and K-Space techniques will be introduced. Laboratories will involve measuring ultrasound image metrics, examining the effect of various beamforming parameters and simulating these on a computer using Matlab. Prerequisite: instructor permission, BIOM 6310 and BIOM 6311. Preparation: Undergraduate Physics, Electronic circuit analysis, Differential Equations, Fourier and Laplace Transforms, Sampling Theorems.
Course was offered Fall 2014, Spring 2011
BME 8782Magnetic Resonance Imaging (3.00)
Offered
Fall 2017
The course covers the physical principles of nuclear magnetic resonance, the biological and medical problems addressed using MRI, the analysis and design of MRI pulse sequences from a signal processing perspective, and MR image reconstruction techniques. It will introduce various advanced topics, including non-Cartesian scanning and compressed sensing. The course will include a laboratory session working with an MRI scanner. Prerequisites: BME 6311 BME Measurement Principles, or knowledge of 2D Fourier transforms and linear systems theory.
Course was offered Spring 2016, Fall 2013, Fall 2010
BME 8783Advanced Magnetic Resonance Imaging (3.00)
Advanced physics and applications of magnetic resonance imaging and spectroscopy will be covered. Upon completion of this course, the student will understand the factors that affect the MRI signal, and will know how these factors can be exploited to image or measure various aspects of physiology with MR. Prerequisites: BME 8782 Magnetic Resonance Imaing and MATLAB experience.
Course was offered Spring 2017, Spring 2011
BME 8823Cell Mechanics, Adhesion, and Locomotion (3.00)
Biomechanics and structural biology of cell structure and function, focusing on quantitative description and measurements of cell deformability, adhesion, and locomotion. Cell deformability: erythrocyte properties, membrane mechanics, shear, bending, and area elasticity. Leukocyte structure and deformability. Structural basis of plasma membrane, lipid bilayer, surface structures, nucleus, organelles, cell junctions, cytoskeleton, membrane transport, active cytoskeletal functions, specific and non-specific forces between molecules, protein structure, molecular graphics. Cell adhesion molecules: families of adhesion molecules, cell-cell and cell-matrix binding, biochemical characteristics, regulation of expression, regulation of binding avidity, functional role. Cell adhesion assays: detachment assays, aggregation of leukocytes and platelets, controlled shear systems, flow chambers. Mechanics of cell adhesion: equilibrium analysis of cell adhesion, models of cell rolling, adhesion bond mechanics. Liposomes, microbubbles, and applications to targeted adhesion. Cell motility: measurement of active forces and motility in cells, molecular motors. Effects of mechanical stress and strain on cell function. Prerequisite: Instructor permission.
Course was offered Fall 2009
BME 8890Biomolecular Engineering (3.00)
In this class, students design treatment strategies for cancer and cardiovascular disease based on molecular bioengineering principles. Special topics will include design of nanoparticle drug and gene delivery platforms, materials biocompatibility, cancer immunotherapy, and molecular imaging. Prerequisites: Undergraduate coursework in cell and molecular biology and biomechanics. Recommended undergraduate course in transport processes.
BME 8900Graduate Teaching Instruction (1.00 - 12.00)
For master's students.
Course was offered Fall 2010, Spring 2010, Fall 2009
BME 8995M.E. Supervised Project Research (M.E. STUDENTS ONLY) (1.00 - 6.00)
Offered
Fall 2017
FOR M.E. STUDENTS ONLY. A research project in biomedical engineering conducted in consultation with a faculty advisor. Includes the design, execution, and analysis of experimental laboratory work and computational or theoretical computer analysis of a problem. Fulfills the project requirement for the Biomedical Engineering Masters of Engineering degree. Prerequisites: Instructor Permission Required.
BME 8999Master's Research (1.00 - 12.00)
Offered
Fall 2017
Master's Research
BME 9999Dissertation (1.00 - 12.00)
Offered
Fall 2017
Formal record of student commitment to doctoral research under the guidance of a faculty advisor. May be repeated as necessary.